TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.020 GeneticVariation BEFREE In this study, we examined two TNF promoter variants (rs 1800629 at position -308, and rs361525 at position -238) for TIDM association in 233 patients and 144 controls from the population of South Croatia. 18949133 2008
dbSNP: rs361525
rs361525
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.020 GeneticVariation BEFREE Initially, association with T1D was seen for LT-alpha A1069G (intron A, p=0.011, rs909253) and TNF G(-308)A (p<1x10(-5), rs1800629), but no association was observed for TNF G(-238)A (rs361525). 17174749 2006