Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0029408
Disease:
Degenerative polyarthritis
0.030 GeneticVariation BEFREE The purpose of the present case-control study was to investigate a possible association of four cytokine single nucleotide polymorphisms (SNPs), IL-4R -3223C>T (rs2057768), IL-8 -251T>A (rs4073), IL-10 -1082A>G (rs1800896) and TNF -A-308G>A (rs1800629) with OA susceptibility. 30186498 2018
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0029408
Disease:
Degenerative polyarthritis
0.030 GeneticVariation BEFREE In conclusion, TNF-α rs1800629 polymorphism confers susceptibility to OA, especially among Asians. 29846433 2018
dbSNP: rs1800629
rs1800629
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0029408
Disease:
Degenerative polyarthritis
0.030 GeneticVariation BEFREE The frequencies of the allele 'A' of rs1800629 were 16% and 8.85% in OA cases and in controls, respectively, and thus the -308A allele had a 1.9612-fold (95% CI = 1.3323-2.8869, P < 0.001) increased risk for OA as compared to the -308G allele. 23748461 2013