TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Polycystic Ovary Syndrome ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799724
rs1799724
Entrez Id: 4049;7124
Gene Symbol: LTA;TNF
LTA;TNF
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.020 GeneticVariation BEFREE A significant difference in transmission was found for rs1799964 (transmitted: non-transmitted = 73 : 39; χ(2) = 10.321; P = 0.0013). rs1799724 showed no evidence of an association with PCOS; risk alleles were over transmitted (transmitted: non-transmitted = 43 : 33; χ(2) = 1.316). 25246119 2014
dbSNP: rs1799724
rs1799724
Entrez Id: 4049;7124
Gene Symbol: LTA;TNF
LTA;TNF
CUI: C0032460
Disease:
Polycystic Ovary Syndrome 		0.020 GeneticVariation BEFREE In conclusion, our present results suggest that the TNF-α system might contribute to the pathogenesis of HA, Ob, and IR in PCOS independent of a polymorphism of the TNF-α C850T (rs1799724) in our population. 25083576 2014