TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11540652
rs11540652
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0678222
Disease:
Breast Carcinoma 		0.020 GeneticVariation BEFREE Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient. 26703669 2015
dbSNP: rs11540652
rs11540652
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0678222
Disease:
Breast Carcinoma 		0.020 GeneticVariation BEFREE The R248Q mutant co-localized with amyloid-like species in a breast cancer sample, which further supported its prion-like effect. 22715097 2012