TPH1, tryptophan hydroxylase 1, 7166

N. diseases: 127; N. variants: 11
Disease: Post-Traumatic Stress Disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2108977
rs2108977
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0038436
Disease:
Post-Traumatic Stress Disorder 		0.010 GeneticVariation BEFREE After adjusting for age, sex, exposure and environmental variables, there was a significant association of PTSD symptoms with the 't' allele of TPH1 SNP rs2108977 (p<0.004), explaining 3% of the phenotypic variance. 22483952 2012