TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1049927
rs1049927
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2301241
rs2301241
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0010068
Disease:
Coronary heart disease 		0.700 GeneticVariation GWASDB A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 22319020 2012
dbSNP: rs2301241
rs2301241
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE With respect to acrylamide-gene interactions, only rs1800566 in NAD(P)H quinone dehydrogenase 1 (NQO1) and rs2301241 in thioredoxin (TXN) showed a nominally statistically significant multiplicative interaction with acrylamide intake for advanced prostate cancer risk. 29697282 2019
dbSNP: rs2301241
rs2301241
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE With respect to acrylamide-gene interactions, only rs1800566 in NAD(P)H quinone dehydrogenase 1 (NQO1) and rs2301241 in thioredoxin (TXN) showed a nominally statistically significant multiplicative interaction with acrylamide intake for advanced prostate cancer risk. 29697282 2019
dbSNP: rs2301241
rs2301241
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Six polymorphisms evaluated in the combined set showed significantly modified breast cancer risk per allele in the joint analysis, including SNPs in CYBA (encoding a subunit of the NADPH oxidase: rs3794624), MT2A (metallothionein 2A: rs1580833), TXN (thioredoxin: rs2301241), and in TXN2 (thioredoxin 2: rs2267337, rs2281082, rs4821494). 21792883 2011
dbSNP: rs2301241
rs2301241
Entrez Id: 7295
Gene Symbol: TXN
TXN
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Six polymorphisms evaluated in the combined set showed significantly modified breast cancer risk per allele in the joint analysis, including SNPs in CYBA (encoding a subunit of the NADPH oxidase: rs3794624), MT2A (metallothionein 2A: rs1580833), TXN (thioredoxin: rs2301241), and in TXN2 (thioredoxin 2: rs2267337, rs2281082, rs4821494). 21792883 2011