UBE2I, ubiquitin conjugating enzyme E2 I, 7329

N. diseases: 131; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11248866
rs11248866
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0871470
Disease:
Systolic Pressure
A 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019
dbSNP: rs2281226
rs2281226
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0871470
Disease:
Systolic Pressure
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2369842
rs2369842
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0023508
Disease:
White Blood Cell Count procedure
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11553473
rs11553473
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE We observed that a risk of breast cancer occurrence is elevated in patients with the G/A genotype (OR 5.03; 95% Cl 3.05-8.28), the A/A genotype (OR 11.3; 95% Cl 4.24-30.3) and the A allele (OR 6.86; 95% Cl 4.43-10.6) of the c.73G>A polymorphism. 23873416 2014
dbSNP: rs11553473
rs11553473
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0678222
Disease:
Breast Carcinoma
0.020 GeneticVariation BEFREE We observed that a risk of breast cancer occurrence is elevated in patients with the G/A genotype (OR 5.03; 95% Cl 3.05-8.28), the A/A genotype (OR 11.3; 95% Cl 4.24-30.3) and the A allele (OR 6.86; 95% Cl 4.43-10.6) of the c.73G>A polymorphism. 23873416 2014
dbSNP: rs11553473
rs11553473
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0678222
Disease:
Breast Carcinoma
0.020 GeneticVariation BEFREE Our results suggest that the c.73G>A polymorphism of the UBC9 gene may affect DNA DSBs repair efficacy in breast cancer patients. 20863840 2010
dbSNP: rs11553473
rs11553473
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE Our results suggest that the c.73G>A polymorphism of the UBC9 gene may affect DNA DSBs repair efficacy in breast cancer patients. 20863840 2010
dbSNP: rs11553473
rs11553473
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C1527349
Disease:
Ductal Breast Carcinoma
0.010 GeneticVariation BEFREE The aim of this study was to investigate an association between three polymorphisms of the UBC9 gene: c.73G>A (rs11553473), c.430T>G (rs75020906) and g.1289209T>C (rs7187167) and a risk of ductal breast cancer occurrence. 23873416 2014
dbSNP: rs761059
rs761059
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C0002395
Disease:
Alzheimer's Disease
0.010 GeneticVariation BEFREE The genotype distribution of a polymorphism in intron 7 (rs761059) differed between AD cases and controls, with an adjusted odds ratio (OR) of 1.45 (p=0.046, 95% CI: 1.01-2.08). 19765634 2009
dbSNP: rs8052688
rs8052688
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C1270972
Disease:
Mild cognitive disorder
0.010 GeneticVariation BEFREE When the samples were stratified by gender, the genotypes of two SNPs (rs8052688, rs8063) were significantly associated with the risk of MCI among women. 19765634 2009
dbSNP: rs8063
rs8063
Entrez Id: 7329
Gene Symbol: UBE2I
UBE2I
CUI: C1270972
Disease:
Mild cognitive disorder
0.010 GeneticVariation BEFREE When the samples were stratified by gender, the genotypes of two SNPs (rs8052688, rs8063) were significantly associated with the risk of MCI among women. 19765634 2009