VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Disease: Hypertensive disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3025039
rs3025039
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0020538
Disease:
Hypertensive disease 		0.020 GeneticVariation BEFREE Genotype CT of rs3025039, TT of rs2305948, and AA of rs1873077 were associated with a reduced risk of CHD when smoking, alcohol intake and diabetes were considered, while homozygote GG of rs1570360 might elevate the susceptibility to CHD (all P < 0.05) for patients who were addicted to smoking or those with hypertension. 27175642 2016
dbSNP: rs3025039
rs3025039
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0020538
Disease:
Hypertensive disease 		0.020 GeneticVariation BEFREE In this retrospective study, the rs3025039 polymorphism was significantly associated with time to treatment failure and hypertension in patients treated with bevacizumab-based chemotherapy. 25617075 2015