VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Disease: Age related macular degeneration ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3025039
rs3025039
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration 		0.030 GeneticVariation BEFREE Significant associations with AMD risk were showed for rs833061, rs1413711, and rs3025039 polymorphisms but not for rs2010963. 27999450 2016
dbSNP: rs3025039
rs3025039
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration 		0.030 GeneticVariation BEFREE The meta-analysis results based on nine case-control studies with 2427 cases and 2037 controls showed that rs833061 had protective effects on AMD risk (TT vs. CT+CC: OR=0.58, 95% CI=0.41-0.81), whereas rs1413711 (TT vs. CT+CC: OR=1.46, 95% CI=1.10-1.93) and rs3025039 (TT vs. CC: OR=1.87, 95% CI=1.15-3.02; TT vs. CT+CC: OR=2.09, 95% CI=1.30-3.37) represented as risk factors for AMD. 24689893 2014
dbSNP: rs3025039
rs3025039
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0242383
Disease:
Age related macular degeneration 		0.030 GeneticVariation BEFREE No association was observed between AMD risk and the variant genotypes of VEGF-A rs2010963 and rs3025039 polymorphisms in different genetic models. 23761723 2013