Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.040 GeneticVariation BEFREE No association is found between the polymorphisms in XRCC1 (Arg399Gln, Arg280His, and Arg194Trp) and risk of colorectal cancer. 20033188 2010
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.040 GeneticVariation BEFREE Several potential functional polymorphisms in the DNA repair gene X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln (rs25487), Arg194Trp (rs1799782), Arg280His (rs25489) and X-ray repair cross-complementing group 3 (XRCC3) T241M (rs861539) have been implicated in colorectal cancer (CRC) risk, but the results are conflicting. 23271134 2013
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.040 GeneticVariation BEFREE Several potential functional polymorphisms in the DNA repair gene X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln (rs25487), Arg194Trp (rs1799782), Arg280His (rs25489) and X-ray repair cross-complementing group 3 (XRCC3) T241M (rs861539) have been implicated in colorectal cancer (CRC) risk, but the results are conflicting. 23271134 2013
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.040 GeneticVariation BEFREE The Arg280His polymorphism modified the association between alcohol consumption and colorectal cancer risk (interaction P = 0.049). 22186158 2012
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0009402
Disease:
Colorectal Carcinoma
0.040 GeneticVariation BEFREE Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His, Asp148Glu; OGG1 Ser236Cys; PARP Val742Ala; and XRCC1 Arg194Trp, Arg280His, Arg399Gln) as potential CRC risk factors and modifiers of the association between diets high in red meat or poultry and CRC risk. 21037106 2010