XRCC1, X-ray repair cross complementing 1, 7515

N. diseases: 410; N. variants: 39
Disease: Malignant neoplasm of stomach ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799782
rs1799782
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE However, significant associations between Arg194Trp polymorphism and gastric cancer were found in Asian. 25335737 2014
dbSNP: rs25487
rs25487
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE Our meta-analysis indicates that genetic polymorphism of the XRCC1 Arg399Gln and Arg280His do not have an association with gastric cancer risk. 25335737 2014
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.060 GeneticVariation BEFREE Our meta-analysis indicates that genetic polymorphism of the XRCC1 Arg399Gln and Arg280His do not have an association with gastric cancer risk. 25335737 2014
dbSNP: rs377566281
rs377566281
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE In addition to tumour stage, which is an important prognostic factor affecting to the survival of stomach cancer patients, the genetic variant Gln339Arg in XRCC1 may non-significantly contribute to risk of stomach cancer death among Thai people. 26320504 2015
dbSNP: rs25487
rs25487
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE Our findings demonstrated that XRCC1 gene rs25487 polymorphism might play a leading role in pronounced susceptibility to gastric cancer in Han Chinese. 26590607 2016
dbSNP: rs25487
rs25487
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE We additionally found that the variant 399Gln allele in Arg399Gln SNP was associated with a greater risk of developing gastric cancer. 27221877 2016
dbSNP: rs1799782
rs1799782
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE In conclusion, we suggest that the XRCC1 gene Arg194Trp polymorphism is associated with gastric cancer susceptibility in the Chinese population. 27706710 2016
dbSNP: rs25487
rs25487
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE However, the XRCC1 Arg399Gln and Arg280His polymorphisms were shown to have no influence on the development of gastric cancer. 27706710 2016
dbSNP: rs25489
rs25489
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.060 GeneticVariation BEFREE However, the XRCC1 Arg399Gln and Arg280His polymorphisms were shown to have no influence on the development of gastric cancer. 27706710 2016
dbSNP: rs25487
rs25487
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.100 GeneticVariation BEFREE However, we did not find any association of polymorphism of XRCC1 Arg399Gln (OR = 1.56; 95% CI: 0.32-7.82) and XPD Lys751Gln (OR = 0.46; CI: 0.10-2.19) with GC risk in the study population. 30225185 2018