XRCC3, X-ray repair cross complementing 3, 7517

N. diseases: 184; N. variants: 24
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs149642280
rs149642280
Entrez Id: 3831;7517
Gene Symbol: KLC1;XRCC3
KLC1;XRCC3
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE In contrast, cells carrying the XRCC3 D213N variant are able to eliminate aberrant cells by apoptosis, and consistent with this observation, this variant does not seem to be associated with cancer susceptibility. 16505003 2006
dbSNP: rs149642280
rs149642280
Entrez Id: 3831;7517
Gene Symbol: KLC1;XRCC3
KLC1;XRCC3
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE Thus we have no evidence that D213N increases the risk of cancer. 12668615 2003