PALB2, partner and localizer of BRCA2, 79728

N. diseases: 260; N. variants: 410
Disease: Malignant neoplasm of breast ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. 26786923 2016
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. 26315354 2015
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. 24556621 2014
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR PALB2: the hub of a network of tumor suppressors involved in DNA damage responses. 24998779 2014
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575 2014
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada. 25225577 2014
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. 19584259 2009
dbSNP: rs587776428
rs587776428
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0006142
Disease:
Malignant neoplasm of breast 		T 0.700 GeneticVariation CLINVAR PALB2 regulates recombinational repair through chromatin association and oligomerization. 19423707 2009