PALB2, partner and localizer of BRCA2, 79728

N. diseases: 260; N. variants: 410
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland. 28279176 2017
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients. 28724667 2017
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis. 25959805 2015
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR The PALB2 gene is a strong candidate for clinical testing in BRCA1- and BRCA2-negative hereditary breast cancer. 24136930 2013
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Rare occurrence of PALB2 mutations in ovarian cancer patients from the Volga-Ural region. 22310028 2012
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer. 21285249 2011
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer. 21618343 2011
dbSNP: rs180177143
rs180177143
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. 19264984 2009