TFPI2, tissue factor pathway inhibitor 2, 7980

N. diseases: 161; N. variants: 5
Disease: Fibrosarcoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs765431049
rs765431049
Entrez Id: 2792;7980;105375401
Gene Symbol: GNGT1;TFPI2;LOC105375401
GNGT1;TFPI2;LOC105375401
CUI: C0016057
Disease:
Fibrosarcoma 		0.010 GeneticVariation BEFREE To directly assess its role in tumor growth and metastasis in vivo, we stably transfected HT-1080 fibrosarcoma cells expressing either fully active wild-type human TFPI-2 (WT) or inactive R24Q TFPI-2 (QT) and examined their ability to form tumors and metastasize in athymic mice in comparison to mock-transfected cells (MT). 14525759 2004