CLPTM1L, CLPTM1 like, 81037

N. diseases: 110; N. variants: 20
Disease: Primary malignant neoplasm of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs31489
rs31489
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.050 GeneticVariation BEFREE Overall, significantly elevated LC risk was associated with rs2736100, rs401681, rs402710, and rs31489 polymorphisms when all studies were pooled into the meta-analysis. 24615522 2014
dbSNP: rs31489
rs31489
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.050 GeneticVariation BEFREE In conclusion, this meta-analysis suggested that CLPTM1L rs31489 was a potential biomarker for lung cancer risk in Caucasians. 24535780 2014
dbSNP: rs31489
rs31489
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.050 GeneticVariation BEFREE Overall, the findings from our replication study and meta-analysis demonstrated that CLPTM1L gene rs31489 is significantly associated with lung cancer. 25422207 2014
dbSNP: rs31489
rs31489
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.050 GeneticVariation BEFREE The rs31489 variant on 5p15.33 is associated with bronchial obstruction, presence and severity of emphysema, and lung cancer. 21622582 2011
dbSNP: rs31489
rs31489
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.050 GeneticVariation BEFREE SNP rs31489 showed the strongest evidence of familial lung cancer association on 5p15.33 (P = 2 x 10(-4); odds ratio, 0.57; 95% confidence interval, 0.42-0.77), whereas rs3117582 showed a weak association on 6p21.33 (P = 0.09; odds ratio, 1.47; 95% confidence interval, 0.94-2.31). 20142248 2010