GDF5, growth differentiation factor 5, 8200

N. diseases: 238; N. variants: 24
Disease: Lumbar disc disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs143383
rs143383
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
CUI: C0221775
Disease:
Lumbar disc disease 		0.020 GeneticVariation BEFREE In conclusion, CC mutant type at rs143383 in <i>GDF5</i> gene has a strong association with the incidence of LDD, and a high prevalence risk, but it has no evident correlation with pathological grades. 30186416 2018
dbSNP: rs143383
rs143383
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
CUI: C0221775
Disease:
Lumbar disc disease 		0.020 GeneticVariation BEFREE An association between LDD and the SNP rs143383 was identified in women, with the same risk allele as in knee and hip OA (odds ratio 1.72 [95% confidence interval 1.15-2.57], P = 0.008). 21360499 2011