CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045485
rs1045485
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE Association of caspase 8 polymorphisms -652 6N InsDel and Asp302His with progression-free survival and tumor infiltrating lymphocytes in early breast cancer. 31467295 2019
dbSNP: rs1045485
rs1045485
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE A missense SNP in exon 10 of the CASP8 gene SNP D302H was associated with worse overall and event-free survival in patients with MYCN-amplified neuroblastoma tumors. 25502557 2014
dbSNP: rs1045485
rs1045485
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0027651
Disease:
Neoplasms 		0.030 GeneticVariation BEFREE The two candidate loci, CASP8 (rs1045485, rs17468277) and TGFB1 (rs1982073), were most strongly related with the risk of PR negative tumors (P = 5.1 × 10(-6) and P = 4.1 × 10(-4), respectively), as previously suggested. 21596841 2011