KIAA1109, KIAA1109, 84162

N. diseases: 86; N. variants: 30
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11938795
rs11938795
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.010 GeneticVariation BEFREE The allelic variants T in rs11938795 and G in rs6822844 were significantly associated with a higher risk of CRC. 31519598 2019
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0004943
Disease:
Behcet Syndrome 		0.010 GeneticVariation BEFREE Moreover, gender susceptibility for uveitis might be involved in the KIAA1109 gene and the KIAA1109-rs4505848 polymorphism might be associated with the development of Behçet's disease. 22876110 2012
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0042167
Disease:
Uveitis, Posterior 		0.010 GeneticVariation BEFREE Our results demonstrated that CFH-rs800292 and KIAA1109-rs4505848 are associated with non-infectious intermediate and posterior uveitis. 22876110 2012
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0042164
Disease:
Uveitis 		0.010 GeneticVariation BEFREE Moreover, gender susceptibility for uveitis might be involved in the KIAA1109 gene and the KIAA1109-rs4505848 polymorphism might be associated with the development of Behçet's disease. 22876110 2012
dbSNP: rs13151961
rs13151961
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0566602
Disease:
Primary sclerosing cholangitis 		0.010 GeneticVariation BEFREE The minor alleles of all four markers were associated with a decreased susceptibility to PSC (rs13151961: p = 0.013, odds ratio (OR) 0.34; rs13119723: p = 0.023, OR 0.40; rs6822844: p = 0.031, OR 0.41; rs6840978: p = 0.043, OR 0.46). 21304239 2011
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0701807
Disease:
Acute anterior uveitis 		0.010 GeneticVariation BEFREE No significant association was found between AU and KIAA1109-rs45</span>05848 or IL27-rs4788084 even stratified by gender. 22065918 2011
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0042165
Disease:
Anterior uveitis 		0.010 GeneticVariation BEFREE No significant association was found between AU and KIAA1109-rs45</span>05848 or IL27-rs4788084 even stratified by gender. 22065918 2011
dbSNP: rs13119723
rs13119723
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE However, we found suggestive evidence for a significant association between the presence of the rs13119723 variant (located in a protein of unknown function) and men with a family history of prostate cancer in first-degree relatives (P-value for interaction 0.02). 20184734 2010
dbSNP: rs13119723
rs13119723
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE However, we found suggestive evidence for a significant association between the presence of the rs13119723 variant (located in a protein of unknown function) and men with a family history of prostate cancer in first-degree relatives (P-value for interaction 0.02). 20184734 2010
dbSNP: rs11938795
rs11938795
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0010346
Disease:
Crohn Disease 		0.010 GeneticVariation BEFREE Another marker, rs11938795, also showed evidence of an association with CD (P=0.006; OR (95% CI)=0.73 (0.58-0.92)). 19471255 2009
dbSNP: rs13151961
rs13151961
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0009324
Disease:
Ulcerative Colitis 		0.010 GeneticVariation BEFREE All four SNPs were strongly associated with UC in all three cohorts and reached genome-wide significance in the pooled analysis (rs13151961 p = 1.35 x 10(-10), rs13119723 p = 8.60 x 10(-8), rs6840978 p = 3.0 7x 10(-8), rs6822844 p = 2.77 x 10(-9)). 19201773 2009
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE For IL-21, rs6822844 and rs4505848 were described to have significant associations with susceptibility to RA. 31454755 2020
dbSNP: rs13119723
rs13119723
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0009324
Disease:
Ulcerative Colitis 		0.020 GeneticVariation BEFREE All four SNPs were strongly associated with UC in all three cohorts and reached genome-wide significance in the pooled analysis (rs13151961 p = 1.35 x 10(-10), rs13119723 p = 8.60 x 10(-8), rs6840978 p = 3.0 7x 10(-8), rs6822844 p = 2.77 x 10(-9)). 19201773 2009
dbSNP: rs13119723
rs13119723
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0009324
Disease:
Ulcerative Colitis 		0.020 GeneticVariation BEFREE Three of the five celiac disease risk markers had a protective effect on UC susceptibility, and this effect remained significant after correcting for multiple testing: rs6840978: P=0.0082, P(corr)=0.049, odds ratio (OR) 0.77, 95% confidence interval (CI) 0.63-0.93; rs6822844: P=0.0028, P(corr)=0.017, OR 0.73, 95% CI 0.59-0.90; rs13119723: P=0.0058, P(corr)=0.035, OR 0.75, 95% CI 0.61-0.92. 19455118 2009
dbSNP: rs4505848
rs4505848
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.020 GeneticVariation BEFREE We observed evidence for association of the heterozygous rs4505848-AG genotype with rheumatoid arthritis (P = 0.04); however, no significance was found after Bonferroni correction. 19302705 2009
dbSNP: rs138538714
rs138538714
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0004096
Disease:
Asthma 		C 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs45510091
rs45510091
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C1269683
Disease:
Major Depressive Disorder 		A 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901 2019
dbSNP: rs45609335
rs45609335
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs45613035
rs45613035
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0004096
Disease:
Asthma 		C 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs45613035
rs45613035
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0013595
Disease:
Eczema 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs45613035
rs45613035
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0004096
Disease:
Asthma 		C 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs368227278
rs368227278
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C4693347
Disease:
ALKURAYA-KUCINSKAS SYNDROME 		0.700 GeneticVariation UNIPROT KIAA1109 Variants Are Associated with a Severe Disorder of Brain Development and Arthrogryposis. 29290337 2018
dbSNP: rs45605540
rs45605540
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C1527304
Disease:
Allergic Reaction 		0.700 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011 2018
dbSNP: rs45605540
rs45605540
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C0004096
Disease:
Asthma 		0.700 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011 2018
dbSNP: rs77087420
rs77087420
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
CUI: C1269683
Disease:
Major Depressive Disorder 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085 2018