After adjusting for other co-variants, the individuals carrying RECK promoter rs10814325 inheriting at least one C allele had a 1.85-fold [95% confidence interval (CI), 1.03-3.36] risk of developing HCC compared to TT wild type carriers.
The rs16932912(G/A) SNP in the RECK gene was closely associated with active proliferation, capsular invasion, and clinical recurrence of ameloblastoma.
The rs16932912(G/A) SNP in the RECK gene was closely associated with active proliferation, capsular invasion, and clinical recurrence of ameloblastoma.
RECK gene rs10814325 T>C could not be considered a risk factor for HCC development on top of HCV, but may be related to the disease progression and metastasis.
We found that the G allele of rs11788747 in the RECK gene was significantly associated with WT in Chinese children (OR=0.7, 95% CI: 0.45-0.99; P=0.042); as with another SNP rs10972727, however, no statistically significant difference was detected.
We found that the G allele of rs11788747 in the RECK gene was significantly associated with WT in Chinese children (OR=0.7, 95% CI: 0.45-0.99; P=0.042); as with another SNP rs10972727, however, no statistically significant difference was detected.
Haplotypes analyses showed that the A(rs11788747)-G(rs16932912)-C(rs10814325) and A(rs11788747)-A(rs16932912A)-C(rs10814325) were associated with higher risk for NSCLC; however, G(rs11788747)-G(rs16932912)-T(rs10814325) and G(rs11788747)-A(rs16932912)-T(rs10814325) haplotypes showed significantly protective roles in the NSCLC risk.
Haplotypes analyses showed that the A(rs11788747)-G(rs16932912)-C(rs10814325) and A(rs11788747)-A(rs16932912A)-C(rs10814325) were associated with higher risk for NSCLC; however, G(rs11788747)-G(rs16932912)-T(rs10814325) and G(rs11788747)-A(rs16932912)-T(rs10814325) haplotypes showed significantly protective roles in the NSCLC risk.
Haplotypes analyses showed that the A(rs11788747)-G(rs16932912)-C(rs10814325) and A(rs11788747)-A(rs16932912A)-C(rs10814325) were associated with higher risk for NSCLC; however, G(rs11788747)-G(rs16932912)-T(rs10814325) and G(rs11788747)-A(rs16932912)-T(rs10814325) haplotypes showed significantly protective roles in the NSCLC risk.
In 263 betel quid chewing oral cancer patients, RECK rs10814325 polymorphism have a 2.26-fold (95% CI, 1.19-4.29) risk to have neck lymph node metastasis compared with RECK wild-type carrier.