MEGF10, multiple EGF like domains 10, 84466

N. diseases: 41; N. variants: 17
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs143954261
rs143954261
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C0002395
Disease:
Alzheimer's Disease 		0.800 GeneticVariation GWASDB Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
dbSNP: rs143954261
rs143954261
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C0002395
Disease:
Alzheimer's Disease 		0.800 GeneticVariation GWASCAT Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. 23535033 2014
dbSNP: rs387907072
rs387907072
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.800 GeneticVariation UNIPROT Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes. 27170117 2016
dbSNP: rs387907073
rs387907073
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.700 GeneticVariation UNIPROT Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes. 27170117 2016
dbSNP: rs387907074
rs387907074
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.700 GeneticVariation UNIPROT Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes. 27170117 2016
dbSNP: rs387907072
rs387907072
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.800 GeneticVariation UNIPROT Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions. 28498977 2017
dbSNP: rs387907073
rs387907073
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.700 GeneticVariation UNIPROT Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions. 28498977 2017
dbSNP: rs387907074
rs387907074
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C3280679
Disease:
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET 		0.700 GeneticVariation UNIPROT Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions. 28498977 2017
dbSNP: rs2194079
rs2194079
Entrez Id: 84466;105379199
Gene Symbol: MEGF10;LOC105379199
MEGF10;LOC105379199
CUI: C0004352
Disease:
Autistic Disorder 		0.010 GeneticVariation BEFREE Our results indicate that three single nucleotide polymorphisms (SNPs), rs4836316, rs2194079 and rs4836317 near the TSS are significantly associated with autism following Bonferroni correction (p = 0.0011, p = 0.0088, and p = 0.0023, respectively). 28536440 2017
dbSNP: rs4836316
rs4836316
Entrez Id: 84466;105379199
Gene Symbol: MEGF10;LOC105379199
MEGF10;LOC105379199
CUI: C0004352
Disease:
Autistic Disorder 		0.010 GeneticVariation BEFREE Our results indicate that three single nucleotide polymorphisms (SNPs), rs4836316, rs2194079 and rs4836317 near the TSS are significantly associated with autism following Bonferroni correction (p = 0.0011, p = 0.0088, and p = 0.0023, respectively). 28536440 2017
dbSNP: rs4836317
rs4836317
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C0004352
Disease:
Autistic Disorder 		0.010 GeneticVariation BEFREE Our results indicate that three single nucleotide polymorphisms (SNPs), rs4836316, rs2194079 and rs4836317 near the TSS are significantly associated with autism following Bonferroni correction (p = 0.0011, p = 0.0088, and p = 0.0023, respectively). 28536440 2017
dbSNP: rs72790443
rs72790443
Entrez Id: 84466
Gene Symbol: MEGF10
MEGF10
CUI: C0036341
Disease:
Schizophrenia 		T 0.700 GeneticVariation GWASCAT Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. 29503163 2018