rs8133843
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
A
0.800
GeneticVariation
GWASCAT
Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.
30423114
2019
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Utility and limitations of exome sequencing in the molecular diagnosis of pediatric inherited platelet disorders.
28960434
2018
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Application of whole-exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia.
28748566
2017
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders.
27112265
2016
rs9979383
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
0.800
GeneticVariation
GWASCAT
Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis.
26546613
2016
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Analyses of Genetic and Clinical Parameters for Screening Patients With Inherited Thrombocytopenia with Small or Normal-Sized Platelets.
26175287
2015
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Biological Activities of RUNX1 Mutants Predict Secondary Acute Leukemia Transformation from Chronic Myelomonocytic Leukemia and Myelodysplastic Syndromes.
25840971
2015
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Biological Activities of RUNX1 Mutants Predict Secondary Acute Leukemia Transformation from Chronic Myelomonocytic Leukemia and Myelodysplastic Syndromes.
25840971
2015
rs9979383
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
A
0.800
GeneticVariation
GWASCAT
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
24532676
2015
rs8133843
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
A
0.800
GeneticVariation
GWASDB
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
24390342
2014
rs8133843
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
A
0.800
GeneticVariation
GWASCAT
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
24390342
2014
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.
23848403
2013
rs16993221
RUNX1;LOC100506403
White Blood Cell Count procedure
A
0.800
GeneticVariation
GWASCAT
Genetic associations with C-reactive protein level and white blood cell count in the KARE study.
22788528
2013
rs16993221
RUNX1;LOC100506403
White Blood Cell Count procedure
A
0.800
GeneticVariation
GWASDB
Genetic associations with C-reactive protein level and white blood cell count in the KARE study.
22788528
2013
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
RUNX1 meets MLL: epigenetic regulation of hematopoiesis by two leukemia genes.
23817177
2013
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.
23848403
2013
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Functional features of RUNX1 mutants in acute transformation of chronic myeloid leukemia and their contribution to inducing murine full-blown leukemia.
22318203
2012
rs9979383
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
0.800
GeneticVariation
GWASCAT
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012
rs9979383
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Rheumatoid Arthritis
0.800
GeneticVariation
GWASDB
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.
17290219
2007
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis.
11830488
2002
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis.
11830488
2002
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
CausalMutation
CLINVAR
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.
10508512
1999
rs1060499616
RUNX1;LOC112267915
Platelet Disorder, Familial, with Associated Myeloid Malignancy
T
0.800
GeneticVariation
CLINVAR
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.
10508512
1999
rs74315450
×
Entrez Id:
861
Gene Symbol:
RUNX1
RUNX1
Platelet Disorder, Familial, with Associated Myeloid Malignancy
0.800
GeneticVariation
UNIPROT
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.
10508512
1999