NRP1, neuropilin 1, 8829

N. diseases: 246; N. variants: 13
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0039685
Disease:
Tetralogy of Fallot 		0.820 GeneticVariation BEFREE The meta-analysis showed that the T allele of the NRP1 polymorphism rs2228638 was significantly associated with an increased risk of TOF in the combined population, which included European and Chinese Han individuals [combined p < 0.00001, odds ratio (OR) = 1.53, 95% confidence interval (95% CI) = 1.35-1.73]. 29432830 2018
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0039685
Disease:
Tetralogy of Fallot 		0.820 GeneticVariation BEFREE We found that rs2228638 in NRP1 on 10p11 was significantly increased the risk of TOF (OR = 1.52, 95% CI = 1.13-2.04, P = 0.006), but not in other subgroups including ASD and VSD. 24594544 2014
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0039685
Disease:
Tetralogy of Fallot 		A 0.820 GeneticVariation GWASDB Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. 23297363 2013
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0039685
Disease:
Tetralogy of Fallot 		A 0.820 GeneticVariation GWASCAT Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. 23297363 2013
dbSNP: rs2506142
rs2506142
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0149931
Disease:
Migraine Disorders 		0.710 GeneticVariation BEFREE Of these SNPs, rs2506142 located near the neuropilin 1 gene (NRP1), was found to be significantly associated with menstrual migraine (p = 0.003). 29671086 2018
dbSNP: rs2506142
rs2506142
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0149931
Disease:
Migraine Disorders 		G 0.710 GeneticVariation GWASCAT Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. 27322543 2016
dbSNP: rs10827226
rs10827226
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0205682
Disease:
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2474714
rs2474714
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0205682
Disease:
Waist-Hip Ratio 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs2247015
rs2247015
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs2253918
rs2253918
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs2506149
rs2506149
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs17296436
rs17296436
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs17296443
rs17296443
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs10827209
rs10827209
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0019693
Disease:
HIV Infections 		0.700 GeneticVariation GWASCAT Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202. 26148204 2015
dbSNP: rs10827209
rs10827209
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0373595
Disease:
Creatinine clearance measurement 		0.700 GeneticVariation GWASCAT Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202. 26148204 2015
dbSNP: rs10080
rs10080
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0039685
Disease:
Tetralogy of Fallot 		0.010 GeneticVariation BEFREE In addition, the association analysis suggested for the first time that there is a strong association between the allele distribution of rs10080 and susceptibility to TOF (p = 0.001). 29432830 2018
dbSNP: rs748899944
rs748899944
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0339573
Disease:
Glaucoma, Primary Open Angle 		0.010 GeneticVariation BEFREE TLR4 coding SNPs Asp299Gly and Thr399Ile might be used as genetic susceptibility alleles for POAG in Mexican population. 28214954 2017
dbSNP: rs894220185
rs894220185
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE Our findings suggested that EGF A61G gene variations and EGF serum levels might be associated with the risk of gastric cancer. 25964549 2015
dbSNP: rs894220185
rs894220185
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE Our findings suggested that EGF A61G gene variations and EGF serum levels might be associated with the risk of gastric cancer. 25964549 2015
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0018818
Disease:
Ventricular Septal Defects 		0.010 GeneticVariation BEFREE We found that rs2228638 in NRP1 on 10p11 was significantly increased the risk of TOF (OR = 1.52, 95% CI = 1.13-2.04, P = 0.006), but not in other subgroups including ASD and VSD. 24594544 2014
dbSNP: rs2228638
rs2228638
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
CUI: C0018817
Disease:
Atrial Septal Defects 		0.010 GeneticVariation BEFREE We found that rs2228638 in NRP1 on 10p11 was significantly increased the risk of TOF (OR = 1.52, 95% CI = 1.13-2.04, P = 0.006), but not in other subgroups including ASD and VSD. 24594544 2014