KAT2B, lysine acetyltransferase 2B, 8850

N. diseases: 116; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12636078
rs12636078
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12636078
rs12636078
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2623079
rs2623079
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4858758
rs4858758
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019
dbSNP: rs2948094
rs2948094
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs2948097
rs2948097
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs4858757
rs4858757
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs12636078
rs12636078
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs12636078
rs12636078
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs9829896
rs9829896
Entrez Id: 8850;100422901
Gene Symbol: KAT2B;MIR3135A
KAT2B;MIR3135A
CUI: C0236969
Disease:
Substance-Related Disorders 		0.700 GeneticVariation GWASCAT KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. 26202629 2016
dbSNP: rs9874923
rs9874923
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0428886
Disease:
Mean blood pressure 		T 0.700 GeneticVariation GWASCAT Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9. 24376456 2013
dbSNP: rs9874923
rs9874923
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0001948
Disease:
Alcohol consumption 		T 0.700 GeneticVariation GWASCAT Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9. 24376456 2013
dbSNP: rs17006625
rs17006625
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C2239176
Disease:
Liver carcinoma 		0.020 GeneticVariation BEFREE Conversely, the HCC risk was higher in patients with the KAT2B rs17006625 GG (OR = 1.64, 95%CI: 1.01-2.64, P = 0.04). 27350734 2016
dbSNP: rs17006625
rs17006625
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C2239176
Disease:
Liver carcinoma 		0.020 GeneticVariation BEFREE The aim of the current study was to assess the impact of the Ile997Val in EP300 and Asn386Ser in PCAF polymorphisms on the risk of HCC. 22709982 2012
dbSNP: rs9829896
rs9829896
Entrez Id: 8850;100422901
Gene Symbol: KAT2B;MIR3135A
KAT2B;MIR3135A
CUI: C0013146
Disease:
Drug abuse 		0.010 GeneticVariation BEFREE Our study identified the KAT2B SNP rs9829896 as having novel and biologically plausible associations with drug abuse and gene expression in AAs but not EAs, suggesting ancestry-specific effects. 26202629 2016
dbSNP: rs17006625
rs17006625
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0017638
Disease:
Glioma 		0.010 GeneticVariation BEFREE Moreover, the frequency of the Asn386Ser allele that contained Ser386 in glioma patients was not statistically different from its frequency in individuals without disease, and no significant association was observed between the PCAF polymorphisms and the presence or absence of p53 mutations in the tumors. 10896202 2000
dbSNP: rs17006625
rs17006625
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Moreover, the frequency of the Asn386Ser allele that contained Ser386 in glioma patients was not statistically different from its frequency in individuals without disease, and no significant association was observed between the PCAF polymorphisms and the presence or absence of p53 mutations in the tumors. 10896202 2000