|
rs2701448
|
TRPA1;MSC-AS1
|
Personality Traits
|
A |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of personality traits in the long life family study.
|
23658558 |
2013 |
|
rs398123010
|
TRPA1;MSC-AS1
|
EPISODIC PAIN SYNDROME, FAMILIAL, 1
|
|
0.700 |
GeneticVariation |
UNIPROT |
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome.
|
20547126 |
2010 |
|
rs920829
|
TRPA1;MSC-AS1
|
Anemia, Sickle Cell
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified that rs920829 (incident rate ratio = 1.44, p = 0.027 additive; IRR=1.68, p=0.008 recessive models of negative binomial regression) and the CGAGG haplotype of TRPA1 (odds ratio = 0.218, p = 0.009) were significantly associated with utilization rate, suggesting that TRPA1 gene polymorphisms may influence acute pain crisis in SCD.
|
29620434 |
2018 |
|
rs1384001
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs3735945
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs4738202
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs7010969
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs920829
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs959974
|
TRPA1;MSC-AS1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
In ALSPAC, there was strong evidence for association between six SNPs and asthma: rs959974 and rs1384001 (per-allele odds ratio for both: 1.30 (95% CI: 1.15-1.47), p = 0.00001), rs7010969 (OR 1.28 (1.13-1.46), p = 0.00004), rs3735945 (OR 1.30 (1.09-1.55), p = 0.003), rs920829 (OR 1.30 (1.09-1.54), p = 0.004) and rs4738202 (OR 1.22 (1.07-1.39), p = 0.004).
|
27779810 |
2017 |
|
rs11988795
|
TRPA1;MSC-AS1
|
Pain
|
|
0.010 |
GeneticVariation |
BEFREE |
Olfactory function and nociception was compared between carriers (n = 38) and non-carriers (n = 43) of TRPA1 variant rs11988795 G>A, a variant known to enhance cold pain perception.
|
24752136 |
2014 |
|
rs200192163
|
TRPA1;MSC-AS1
|
Pain
|
|
0.010 |
GeneticVariation |
BEFREE |
Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor.
|
24975826 |
2014 |
|
rs398123010
|
TRPA1;MSC-AS1
|
Familial (FPAH)
|
|
0.010 |
GeneticVariation |
BEFREE |
Remarkably, a substitution of single amino acid in the S4-S5 region of TRPA1 (N855S) has been recently associated with familial episodic pain syndrome.
|
24564660 |
2014 |
|
rs398123010
|
TRPA1;MSC-AS1
|
Pain Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Remarkably, a substitution of single amino acid in the S4-S5 region of TRPA1 (N855S) has been recently associated with familial episodic pain syndrome.
|
24564660 |
2014 |
|
rs920829
|
TRPA1;MSC-AS1
|
Hypoalgesia
|
|
0.010 |
GeneticVariation |
BEFREE |
However, in neuropathic pain patients transient receptor potential ankyrin 1 710G>A (rs920829, E179K) was associated with the presence of paradoxical heat sensation (p = 0.03), and transient receptor potential vanilloid 1 1911A>G (rs8065080, I585V) with cold hypoalgesia (p = 0.0035).
|
21468319 |
2011 |