SELENBP1, selenium binding protein 1, 8991

N. diseases: 214; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1553204840
rs1553204840
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		0.800 GeneticVariation UNIPROT Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. 29255262 2018
dbSNP: rs758495626
rs758495626
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		0.800 GeneticVariation UNIPROT Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. 29255262 2018
dbSNP: rs1553204840
rs1553204840
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		A 0.800 CausalMutation CLINVAR
dbSNP: rs758495626
rs758495626
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		A 0.800 CausalMutation CLINVAR
dbSNP: rs1357490520
rs1357490520
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		T 0.700 CausalMutation CLINVAR
dbSNP: rs1553204817
rs1553204817
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C4748387
Disease:
EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY 		A 0.700 CausalMutation CLINVAR
dbSNP: rs1012657750
rs1012657750
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs1012657750
rs1012657750
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0242339
Disease:
Dyslipidemias 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs1249051329
rs1249051329
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs1249051329
rs1249051329
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0242339
Disease:
Dyslipidemias 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs771038258
rs771038258
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs771038258
rs771038258
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0242339
Disease:
Dyslipidemias 		0.010 GeneticVariation BEFREE Patients with high Hcy and MTHFR 667CC, as well as those with low Hcy and 667CT+TT, showed lower odds of uncontrolled SBP (MTHFR 667CC+ high Hcy: OR: 0.338, 95% CI: 0.115-0.996, Pcombined = 0.049; MTHFR 667CT/TT+ low Hcy: OR: 0.421, 95% CI: 0.193-0.921, Pcombined = 0.030) compared to patients with low Hcy and MTHFR 667CC.<b>Conclusions</b>: Serum Hcy status and Hcy metabolism gene polymorphisms (MTHFR C667T and MTRR A66G) may have synergistic effects on the prevalence of HTN and dyslipidemia. 30786773 2020
dbSNP: rs1308703978
rs1308703978
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE The other two polymorphic sites (G1258A and A7735G) are not associated with hypertension. 20033074 2010