EXO1, exonuclease 1, 9156

N. diseases: 87; N. variants: 22
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1776148
rs1776148
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Similarly, the rs3754093, rs1776177, rs9350, rs10802996, rs1635498, rs1776148 and rs851797 polymorphisms were also associated with an increased susceptibility to cancer in an allelic model, respectively, while no significant association was identified for rs1635517 polymorphism. 27387683 2016
dbSNP: rs1776177
rs1776177
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs1776177
rs1776177
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs3754093
rs3754093
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs3754093
rs3754093
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs851797
rs851797
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Our findings provide the evidence that the rs1047840, rs9350, rs10802996, rs1635498, rs1776148, rs1776177, rs3754093 and rs851797 polymorphisms may act as risk factors for cancer. 27387683 2016
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE A minor allele of SNP rs9350 in the exonuclease 1 gene was associated with a better response rate, regardless of age and tumor stage (odds ratio, 8.316; p=0.002). 27088619 2016
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0600139
Disease:
Prostate carcinoma
0.010 GeneticVariation BEFREE For the first time, we present evidence that the inherited EXO1 polymorphism rs9350 may have a substantial influence on prosta</span>te cancer risk in Chinese people. 26646562 2016
dbSNP: rs9350
rs9350
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE For the first time, we present evidence that the inherited EXO1 polymorphism rs9350 may have a substantial influence on prosta</span>te cancer risk in Chinese people. 26646562 2016
dbSNP: rs2236918
rs2236918
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1629609
Disease:
Age at menopause
C 0.700 GeneticVariation GWASCAT Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 26414677 2015
dbSNP: rs72755295
rs72755295
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0678222
Disease:
Breast Carcinoma
G 0.700 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625 2015
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0007137
Disease:
Squamous cell carcinoma
0.010 GeneticVariation BEFREE We examined the influence of MLH1 c.-93G>A, MSH2 c.211 + 9C>G, MSH3 c.3133G>A and EXO1 c.1765G>A polymorphisms, involved in DNA mismatch repair (MMR), on head and neck (HN) squamous cell carcinoma (SCC) risk and prognosis. 25598504 2015
dbSNP: rs143546023
rs143546023
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.010 GeneticVariation BEFREE Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1. 24829445 2014
dbSNP: rs143546023
rs143546023
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1. 24829445 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE In conclusion, Exo1 K589E Lys allele may be used as a novel biomarker for ca</span>ncer susceptibility, particularly in smokers. 24810280 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE In conclusion, Exo1 K589E Lys allele may be used as a novel biomarker for ca</span>ncer susceptibility, particularly in smokers. 24810280 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. 24761866 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. 24761866 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1306460
Disease:
Primary malignant neoplasm of lung
0.030 GeneticVariation BEFREE This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. 24761866 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0242379
Disease:
Malignant neoplasm of lung
0.030 GeneticVariation BEFREE This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. 24761866 2014
dbSNP: rs1047840
rs1047840
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C0684249
Disease:
Carcinoma of lung
0.030 GeneticVariation BEFREE This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups. 24761866 2014
dbSNP: rs4149963
rs4149963
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
CUI: C1512409
Disease:
Hepatocarcinogenesis
0.010 GeneticVariation BEFREE Our result demonstrates for the first time that the Exo 1 T439M polymorphism does not have a major role in genetic susceptibility to hepatocarcinogenesis, at least in the population studied here. 22296401 2011