IL1RL1, interleukin 1 receptor like 1, 9173

N. diseases: 54; N. variants: 38
Source: ALL
Variant Gene Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3771180
rs3771180
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806 2018
dbSNP: rs10197862
rs10197862
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
dbSNP: rs13408661
rs13408661
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation BEFREE We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus. 23028483 2013
dbSNP: rs13408661
rs13408661
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASDB Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. 23028483 2013
dbSNP: rs13408661
rs13408661
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASCAT Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. 23028483 2013
dbSNP: rs3771180
rs3771180
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation BEFREE We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus. 23028483 2013
dbSNP: rs10197862
rs10197862
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
dbSNP: rs10197862
rs10197862
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation BEFREE However, a variant in IL1RL1 that is in low linkage disequilibrium with that reported previously was associated with asthma risk after accounting for all variants tested (rs10197862, gene wide P = 0.01). 21150878 2011
dbSNP: rs13408661
rs13408661
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
dbSNP: rs3771180
rs3771180
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
dbSNP: rs3771180
rs3771180
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.810 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
dbSNP: rs950881
rs950881
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0020517
Disease:
Hypersensitivity
0.800 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2017
dbSNP: rs950881
rs950881
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0020517
Disease:
Hypersensitivity
0.800 GeneticVariation GWASDB A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. 23817569 2013
dbSNP: rs1420101
rs1420101
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0750879
Disease:
Eosinophil count result
0.800 GeneticVariation GWASCAT Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 19198610 2009
dbSNP: rs1420101
rs1420101
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0750879
Disease:
Eosinophil count result
0.800 GeneticVariation GWASDB Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 19198610 2009
dbSNP: rs1420101
rs1420101
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0200638
Disease:
Eosinophil count procedure
0.800 GeneticVariation GWASDB Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 19198610 2009
dbSNP: rs1420101
rs1420101
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0200638
Disease:
Eosinophil count procedure
0.800 GeneticVariation GWASCAT Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 19198610 2009
dbSNP: rs1420101
rs1420101
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease:
Asthma
0.700 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806 2018
dbSNP: rs10865050
rs10865050
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0020517
Disease:
Hypersensitivity
0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
dbSNP: rs12470864
rs12470864
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0020517
Disease:
Hypersensitivity
0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
dbSNP: rs13001325
rs13001325
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs13001325
rs13001325
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0010346
Disease:
Crohn Disease
0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs5833013
rs5833013
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0200641
Disease:
Blood basophil count (lab test)
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2017
dbSNP: rs5833013
rs5833013
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0750879
Disease:
Eosinophil count result
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2017
dbSNP: rs5833013
rs5833013
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0200638
Disease:
Eosinophil count procedure
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2017