BMP15, bone morphogenetic protein 15, 9210

N. diseases: 48; N. variants: 18
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17003221
rs17003221
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.010 GeneticVariation BEFREE A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively). 25954833 2015
dbSNP: rs3810682
rs3810682
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.010 GeneticVariation BEFREE A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively). 25954833 2015
dbSNP: rs3810682
rs3810682
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.010 GeneticVariation BEFREE A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively). 25954833 2015
dbSNP: rs79377927
rs79377927
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.010 GeneticVariation BEFREE These results demonstrated that GDF9 c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 rs79377927 (788_789insTCT) were associated with POF in the Chinese Hui population. 25954833 2015
dbSNP: rs79377927
rs79377927
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.010 GeneticVariation BEFREE These results demonstrated that GDF9 c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 rs79377927 (788_789insTCT) were associated with POF in the Chinese Hui population. 25954833 2015
dbSNP: rs104894765
rs104894765
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.010 GeneticVariation BEFREE Interestingly, the Y235C mutation was previously identified in association with POI in women. 24147118 2013
dbSNP: rs141218518
rs141218518
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.010 GeneticVariation BEFREE One variant (F194S), predicted as potentially deleterious, was identified for the first time in a POF patient but also identified in one control. 20364024 2010
dbSNP: rs141218518
rs141218518
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.010 GeneticVariation BEFREE One variant (F194S), predicted as potentially deleterious, was identified for the first time in a POF patient but also identified in one control. 20364024 2010
dbSNP: rs41308602
rs41308602
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085083
Disease:
Ovarian Hyperstimulation Syndrome 		0.010 GeneticVariation BEFREE However, N103S missense mutation is predicted to disrupt the secondary structure of human BMP15 protein and is weakly associated with OHSS. 16788381 2006
dbSNP: rs782609889
rs782609889
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.010 GeneticVariation BEFREE However, three single nucleotide polymorphisms in the BMP15 gene, two in the 5' untranslated region (31T>G and 71C>G) and another in exon 1 (387G>A), were found to be common in both POF and control groups. 17027369 2006
dbSNP: rs782609889
rs782609889
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.010 GeneticVariation BEFREE However, three single nucleotide polymorphisms in the BMP15 gene, two in the 5' untranslated region (31T>G and 71C>G) and another in exon 1 (387G>A), were found to be common in both POF and control groups. 17027369 2006
dbSNP: rs17003221
rs17003221
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.020 GeneticVariation BEFREE It is concluded from the present study that the genotypes CT and TT from BMP15:c.852C>T variation may be risk factors for the development of POI. 31392662 2019
dbSNP: rs17003221
rs17003221
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.020 GeneticVariation BEFREE A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively). 25954833 2015
dbSNP: rs104894767
rs104894767
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.020 GeneticVariation BEFREE BMP15 538G>A was found to be significantly more common in patients with POF compared with controls. 25445105 2014
dbSNP: rs104894767
rs104894767
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.020 GeneticVariation BEFREE BMP15 538G>A was found to be significantly more common in patients with POF compared with controls. 25445105 2014
dbSNP: rs104894767
rs104894767
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0025322
Disease:
Premature Menopause 		0.020 GeneticVariation BEFREE One variant (A180T) was identified among two POF cases, and also in two controls. 20364024 2010
dbSNP: rs104894767
rs104894767
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C0085215
Disease:
Ovarian Failure, Premature 		0.020 GeneticVariation BEFREE One variant (A180T) was identified among two POF cases, and also in two controls. 20364024 2010
dbSNP: rs104894763
rs104894763
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs104894766
rs104894766
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs104894767
rs104894767
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs144392417
rs144392417
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs371418883
rs371418883
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs782375794
rs782375794
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs782379521
rs782379521
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010
dbSNP: rs782516193
rs782516193
Entrez Id: 9210
Gene Symbol: BMP15
BMP15
CUI: C1845294
Disease:
Ovarian Dysgenesis 2 		0.700 GeneticVariation UNIPROT Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure. 19438907 2010