NRXN1, neurexin 1, 9378

N. diseases: 139; N. variants: 41
Disease: Schizophrenia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10490162
rs10490162
Entrez Id: 9378
Gene Symbol: NRXN1
NRXN1
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Based on previous suggestive evidence of an impact on clozapine response in patients with schizophrenia, we conducted an association study of NRXN1 polymorphisms (rs12467557 and rs10490162) with antipsychotic treatment response in 54 patients with schizophrenia in a double blind, placebo-controlled NIMH inpatient crossover trial and examined for association with risk for schizophrenia in independent case-control and family-based clinical cohorts. 24633560 2014