CDH1, cadherin 1, 999

N. diseases: 508; N. variants: 187
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life. 27752808 2016
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300 2015
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers. 25979631 2015
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Germline CDH1 mutations in bilateral lobular carcinoma in situ. 24366306 2014
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. 18427545 2008
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. 17545690 2007
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. 15955779 2005
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR GlobPlot: Exploring protein sequences for globularity and disorder. 12824398 2003
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. 11348595 2001
dbSNP: rs587783048
rs587783048
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 CausalMutation CLINVAR Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families. 11729114 2001