rs1006737, CACNA1C

N. diseases: 27
Disease: Bipolar Disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bipolar Disorder
CUI: C0005586
Disease: Bipolar Disorder
0.900 GeneticVariation BEFREE Our data demonstrate that rs1006737 or genetic variants in linkage disequilibrium with it are functional in the human brain and provide a neurogenetic risk mechanism for bipolar disorder backed by genome-wide evidence. 20679588 2010
Bipolar Disorder
CUI: C0005586
Disease: Bipolar Disorder
0.900 GeneticVariation BEFREE Strong evidence (P=7.0 × 10(-7)) of association at the polymorphism rs1006737 (within CACNA1C, the gene encoding the α-1C subunit of the L-type voltage-gated calcium channel) with the risk of bipolar disorder (BD) has recently been reported in a meta-analysis of three genome-wide association studies of BD, including our BD sample (N=1868) studied within the Wellcome Trust Case Control Consortium. 19621016 2010
Bipolar Disorder
CUI: C0005586
Disease: Bipolar Disorder
0.900 GeneticVariation GWASCAT Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Bipolar Disorder
CUI: C0005586
Disease: Bipolar Disorder
0.900 GeneticVariation GWASDB Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008