rs1006737, CACNA1C

N. diseases: 31
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.720 GeneticVariation BEFREE The single nucleotide polymorphism at rs1006737 in CACNA1C has been associated with both schizophrenia and bipolar disorder and with several intermediate phenotypes that may serve as neurobiological antecedents, linking psychosis to genetic aetiology. 26048451 2016
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.720 GeneticVariation GWASDB Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. 24280982 2015
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.720 GeneticVariation BEFREE Recent genetic studies found the A allele of the variant rs1006737 in the alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene to be over-represented in patients with psychosis, including schizophrenia, bipolar disorder and major depressive disorder. 21078228 2011