rs1010023, PNPLA3

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Fatty Liver Disease
CUI: C4529962
Disease: Fatty Liver Disease
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746 2013
Fatty Liver
CUI: C0015695
Disease: Fatty Liver
0.010 GeneticVariation BEFREE In contrast to their role in hepatic steatosis</span>, CC and TC genotypes of <i>PNPLA3</i> rs1010023 were correlated to significant improvement of homeostasis model assessment index (HOMA-IR) as compared to TT genotype in the CHB+HS group. 28695131 2017
Hepatitis B, Chronic
CUI: C0524909
Disease: Hepatitis B, Chronic
0.010 GeneticVariation BEFREE <i>PNPLA3</i> rs1010023 Predisposes Chronic Hepatitis B to Hepatic Steatosis but Improves Insulin Resistance and Glucose Metabolism. 28695131 2017
Steatohepatitis
CUI: C2711227
Disease: Steatohepatitis
0.010 GeneticVariation BEFREE In contrast to their role in hepatic steatosis</span>, CC and TC genotypes of <i>PNPLA3</i> rs1010023 were correlated to significant improvement of homeostasis model assessment index (HOMA-IR) as compared to TT genotype in the CHB+HS group. 28695131 2017