rs1012068, DEPDC5

N. diseases: 5
Disease: Hepatitis C ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE Recently, two genetic variants, DEPDC5 rs1012068 and MICA rs2596542, were associated with the onset of HCC in Asian subjects with chronic HCV infection. 26517016 2016
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE Also, multiple logistic regression analysis showed that rs5998152 (OR = 2.844, 95% CI 1.333-6.069 and p = 0.007), rs1012068 (OR = 2.793, 95% CI 1.316-5.928 and p = 0.010), age (OR = 1.029, 95% CI 1.001-1.057 and p = 0.041) and HCV genotypes (OR = 0.247, 95% CI 0.097-0.630 and p = 0.003) were independently associated with chronicity of HCV infection. 25551790 2014