rs1042522, TP53

N. diseases: 242
Disease: Acute lymphocytic leukemia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Acute lymphocytic leukemia
CUI: C0023449
Disease: Acute lymphocytic leukemia
0.020 GeneticVariation BEFREE In conclusion, the results suggest that there is no association between TP53 Arg72Pro polymorphism and the risk of leukemia, but the CC genotype may increase the risk of ALL TP53 Arg72Pro polymorphism CC genotype may increase the risk of ALL but is not associated with AML. 27053289 2016
Acute lymphocytic leukemia
CUI: C0023449
Disease: Acute lymphocytic leukemia
0.020 GeneticVariation BEFREE Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor suppression. 23653000 2013