|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The present hospital-based retrospective cohort study aimed to evaluate the influence of <i>TP53</i> Arg72Pro (rs1042522) polymorphism in the clinical outcome of 260 Caucasian patients diagnosed with cervical cancer and treated with concomitant radiotherapy and chemotherapy.
|
29731921 |
2018 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Combined analysis revealed that the genotypes of rs4938723 CT/CC and TP53 Arg72Pro CG/CC had an increased cervical cancer risk (OR = 2.21, 95 % CI = 1.38-3.53).
|
26619844 |
2016 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
A hundred HIV-infected women were examined for HPV detection and its genotypes, as well as the frequencies of the SNPs Arg72Pro and SNP309 and their associations with CC risk factors.
|
25181402 |
2015 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results indicated that the polymorphism in TP53 (rs1042522) might be associated with risk of cervical cancer development in HPV16 infected women.
|
23534750 |
2013 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of the present study was to analyze the association of p53 codon72 (arginine/proline) polymorphism (rs1042522) and Murine Double Minute 2 (MDM2) SNP309 T/G (rs2279744) with the advancement of cervical cancer by using polymerase chain reaction-restriction fragment length polymorphism method followed by direct sequencing.
|
23210739 |
2013 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Arg variant of p53 Arg72Pro is associated with progression of SIL to cervical cancer only in the presence of HPV positivity.
|
23065429 |
2012 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to derive a more precise estimation of the association between p53 codon 72 polymorphism (Arg72Pro, rs1042522 G>C) and cervical cancer risk among Asians.
|
23244080 |
2012 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that a heterozygous TP53 Arg72Pro genotype may contribute to cervical cancer susceptibility.
|
21665181 |
2011 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Women carrying the p53 Arg72Pro or p53 Pro72Pro increased the risk of cervical carcinoma (ORs and 95% CIs being 3.74 (2.65-5.30), 2.23 (1.49-3.34)).
|
19576684 |
2010 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
To better understand the role of this polymorphism in cervical cancer etiology, we investigated the association between p53 R72P and cervical cancer risk in Chinese women from southern Han.
|
20193851 |
2010 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Driven by findings that human papillomavirus (HPV)-induced degradation of p53 differs by a TP53 polymorphism at codon 72 (Pro72Arg), past studies of TP53 genetic variants and cervical cancer have focused on this nonsynonymous polymorphism, with mixed results.
|
19423538 |
2009 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The p53 R72P polymorphism does not influence cervical cancer development in a Portuguese population: a study in exfoliated cervical cells.
|
18205229 |
2008 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese.
|
15036661 |
2004 |
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We failed to confirm earlier reports of increased cervical cancer susceptibility in women who harbor the p53 P72R allele.
|
12142377 |
2002 |