|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Each analysis consistently revealed the 46A allele of ADRB2 46G/A SNP and 4a allele of NOS3 4b/4a SNP to be associated with risk of hypertension.
|
25159081 |
2015 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
CYP2J2 -50 G/T and ADRB2 G46A gene polymorphisms in Saudi subjects with hypertension.
|
22731644 |
2012 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results indicated that 46A/G polymorphism in the β2-AR gene was associated with hypertension susceptibility in Han Chinese population.
|
22763735 |
2012 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Furthermore, Gly16Arg (rs1042713) and Gln27Glu (rs1042714) in the ADRB2 gene were not associated with blood pressure, hypertension or CVD either in the population overall or in women and men separately.
|
21883537 |
2012 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We analyzed β3AR Trp64Arg, β2AR Arg16Gly and UCP1 -3826A>G polymorphisms by the Smart Amplification Process 2 in 222 Japanese subjects without the medication of hypertension, dyslipidemia or diabetes, and investigated the association between the physical and metabolic characteristics and the combination of these polymorphisms.
|
21959333 |
2011 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Stratification analyses by obesity showed that A46G polymorphism was related to the prevalence of hypertension in the obese population (GG vs. AG vs. AA, P<0.001, OR = 1.645, 95%CI [1.258-2.151]).
|
21483652 |
2011 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
There was no statistical association between A46G and hypertension risk in all subjects, Asians or Caucasians.
|
20739939 |
2010 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We revealed that a combination of the Arg16Gly and Glu298Asp polymorphisms in ADRB2 and NOS3, respectively, remarkably increased the risk for hypertension in middle-aged and elderly humans.
|
19373110 |
2009 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease.
|
15797659 |
2005 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate whether polymorphisms in the beta(2)-adrenergic receptor gene (5'LC-Arg19Cys, Arg16Gly, Gln27Glu) are associated with hypertension in patients with or without type 2 diabetes and with the blood pressure levels in normotensive sib pairs.
|
11358945 |
2001 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Gly16Arg was significantly associated with hypertension (P < .03).
|
11775126 |
2001 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In particular, Arg16Gly was shown to be associated with hypertension in black and white subjects.
|
11230287 |
2001 |