rs1045642, ABCB1

N. diseases: 108
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ovarian Carcinoma
CUI: C0029925
Disease: Ovarian Carcinoma
0.040 GeneticVariation BEFREE The best candidates from fine-mapping analysis of 21 ABCB1 SNPs tagging C1236T (rs1128503), G2677T/A (rs2032582), and C3435T (rs1045642) were analysed in 4616 European invasive EOC patients from thirteen Ovarian Cancer Association Consortium (OCAC) studies and The Cancer Genome Atlas (TCGA). 23917080 2013
Ovarian Carcinoma
CUI: C0029925
Disease: Ovarian Carcinoma
0.040 GeneticVariation BEFREE CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin. 21327421 2011
Ovarian Carcinoma
CUI: C0029925
Disease: Ovarian Carcinoma
0.040 GeneticVariation BEFREE We analyzed the allelic frequencies at polymorphic sites G2677T/A and C3435T in ovarian cancer patients with good or poor response to treatment with paclitaxel in combination with carboplatin in order to evaluate their predictive values. 16467099 2006
Ovarian Carcinoma
CUI: C0029925
Disease: Ovarian Carcinoma
0.040 GeneticVariation BEFREE Basal expression of the multidrug resistance gene 1 (MDR-1) is associated with the TT genotype at the polymorphic site C3435T in mammary and ovarian carcinoma cell lines. 12142082 2002