Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Familial Mediterranean Fever
CUI: C0031069
Disease: Familial Mediterranean Fever
0.050 GeneticVariation BEFREE The CT genotype frequency of the C3435T polymorphism (p = 0.003), the CT-GT-CT (C1236T-G2677T/A-C3435T) triple genotype (p = 0.001) and the C-G (C1236T-G2677T/A) haplotype (p = 0.030) were more common in the FMF patients. 24773260 2014
Familial Mediterranean Fever
CUI: C0031069
Disease: Familial Mediterranean Fever
0.050 GeneticVariation BEFREE MDR1 gene C3435T polymorphism enacts an important role on colchicine response in FMF; good response to colchicine treatment was related to the C allele, whereas poor response was related to the T allele in FMF. 24180297 2014
Familial Mediterranean Fever
CUI: C0031069
Disease: Familial Mediterranean Fever
0.050 GeneticVariation BEFREE Forty-eight Turkish patients with FMF treated with colchicine were genotyped for 3435C>T, (-)1A>G, 61A>G, 1199G>A, 1236C>T, 2677G>A, 2677G>T polymorphisms in the P-gp/MDR1 gene and 3435C>T, 1B(-392A>G), 2(15713T>C), 3(23171T>C), 12(21896C>T), 17(15615T>C) polymorphisms in the CYP3A4 gene. 23408444 2013
Familial Mediterranean Fever
CUI: C0031069
Disease: Familial Mediterranean Fever
0.050 GeneticVariation BEFREE Analysis of common MDR1 (ABCB1) gene C1236T and C3435T polymorphisms in Turkish patients with familial Mediterranean fever. 22194207 2011
Familial Mediterranean Fever
CUI: C0031069
Disease: Familial Mediterranean Fever
0.050 GeneticVariation BEFREE Our results indicate that C3435T polymorphism in exon 26 of MDR1 gene is associated with colchicine resistance in nonresponder FMF patients during the common therapy protocol. 21851199 2011