rs1045642, ABCB1

N. diseases: 214
Disease: Adult Acute Myeloblastic Leukemia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Acute Myeloblastic Leukemia
CUI: C0220615
Disease: Adult Acute Myeloblastic Leukemia
0.020 GeneticVariation BEFREE MDR1 C3435T polymorphism influences the development of colon cancer and adult acute myeloid leukemia by the association with transporting carcinogen. 18644389 2008
Adult Acute Myeloblastic Leukemia
CUI: C0220615
Disease: Adult Acute Myeloblastic Leukemia
0.020 GeneticVariation BEFREE The authors conclude that isolated 3435C>T ABCB1 SNP is not a major factor of the genetic susceptibility to adult AML, and that genotyping of this polymorphism does not allow predicting P-gp expression or activity in AML cells. 17038891 2006