rs1045642, ABCB1

N. diseases: 108
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis. 29390571 2018
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE We observed that the ABCB1 C3435T and G2677T/A variants as well as the 3435T-1236T-2677T haplotype significantly increased the risk of CRC. 23746184 2014
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk and interactions between the ABCB1 C-rs3789243-T and C3435T polymorphisms and meat intake in relation to CRC risk (Andersen, BMC Cancer, 2009, 9, 407). 23977225 2014
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE Association between the C3435T polymorphism of ABCB1/MDR1 gene (rs1045642) and colorectal cancer susceptibility : a meta-analysis based on 11,339 subjects. 23504525 2013
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE We found that three functional SNPs (rs1202168, rs1045642 and rs868755) were associated with CRC risk in the German population. 22396794 2012
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE Carriers of the variant allele of MDR1 C3435T exon 26 had a lower risk of CRC than homozygous C-allele carriers (IRR = 0.71 (CI:0.50-1.00)). 19930591 2010
Colorectal Cancer
CUI: C1527249
Disease: Colorectal Cancer
0.070 GeneticVariation BEFREE No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients. 17674045 2008