rs104886003, PIK3CA

N. diseases: 71
Disease: Cervix carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.020 GeneticVariation BEFREE In vivo, XAV939 enhanced the radiosensitivity of cervical cancer xenografts with PIK3CA-E545K with invisible viscera toxicity. 31666350 2020
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.020 GeneticVariation BEFREE The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer. 30547809 2018