rs104886003, PIK3CA

N. diseases: 71
Disease: cervical cancer ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.020 GeneticVariation BEFREE In vivo, XAV939 enhanced the radiosensitivity of cervical cancer xenografts with PIK3CA-E545K with invisible viscera toxicity. 31666350 2020
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.020 GeneticVariation BEFREE These findings provide evidence that the PI3K E542K and E545K/β-catenin/SIRT3 signaling axis regulates glucose metabolism and proliferation in cervical cancers with PIK3CA mutations, suggesting therapeutic targets in the treatment of cervical cancers. 30547809 2018