rs1050450, GPX1

N. diseases: 43
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.030 GeneticVariation BEFREE Our analysis revealed that the GPX1 rs1050450 and MPO rs2107545 were significantly associated with increased risk of carotid plaques in type 2 diabetes mellitus patients. 29383971 2018
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.030 GeneticVariation BEFREE Genotype/allele frequencies of GPx1 + 599C/T and carriage rate showed no association although the odds ratio of GPx1 'C' allele indicated a 1.362 times higher risk of T2DM. 25283363 2015
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.030 GeneticVariation BEFREE The aim of the present study was to test the association between genetic polymorphisms with functional effects on redox regulation: the -262C/T of the catalase gene promoter (rs1001179), the C242T of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase P22phox gene (rs4673), and the 594C/T polymorphism of the glutathione peroxidase gene (rs1050450) and arterial hypertension (AH) in patients with type 2 diabetes. 23701472 2014