Autoimmune Diseases
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|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis demonstrates that BANK1 rs10516487, rs3733197, and rs17266594 polymorphisms are associated with susceptibility to autoimmune diseases.
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28466820 |
2017 |
Diffuse Scleroderma
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|
0.010 |
GeneticVariation
|
BEFREE |
The BANK1 variants were found to be associated with diffuse cutaneous SSc (dcSSc) in both cohorts, providing an odds ratio (OR) of 0.77 for the rs10516487 T rare allele in the combined populations of dcSSc patients as compared with the combined populations of controls (95% confidence interval [95% CI] 0.64-0.93) and an OR of 0.73 (95% CI 0.61-0.87) for the rs3733197 A rare allele.
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19877059 |
2009 |
Encephalitis, St. Louis
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|
0.020 |
GeneticVariation
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BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
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21078628 |
2011 |
Encephalitis, St. Louis
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|
0.020 |
GeneticVariation
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BEFREE |
SLE was associated with frequency of rs548234 (P = 0.010; odds ratio [OR] = 1.298), rs2736340 (P = 2.47 × 10<sup>-5</sup> ; OR = 1.574) and rs10516487 (P = 0.002; OR = 0.642).
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26420661 |
2016 |
Graft-vs-Host Disease
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|
0.010 |
GeneticVariation
|
BEFREE |
The donor rs10516487 (BANK1: B-cell scaffold protein with ankyrin repeats 1) TT genotype was associated with lower risk of sclerotic GVHD (hazard ratio [HR], 0.43; 95% confidence interval [CI], 0.21-0.87; P = .02).
|
27313329 |
2016 |
Hemophilia A
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|
0.010 |
GeneticVariation
|
BEFREE |
We analysed eight SNPs (MAPK9 rs4147385, CSF1R rs17725712, CD44 rs927335, STAT4 rs7574865, IKZF1 rs4917014, ETS1 rs6590330, BANK1 rs17266594 and rs10516487) by Snapshot SNP genotyping assays in 100 haemophilia A patients, including 29 with inhibitors and 71 without inhibitors.
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31149782 |
2019 |
Lupus Erythematosus, Systemic
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|
0.880 |
GeneticVariation
|
BEFREE |
We selected and identified three SNPs of BANK1 associated with SLE (rs17266594, P = 1.949e-10; OR = 1.380; 95% CI: 1.250-1.525; rs10516487, P = 2.642e-13; OR = 1.317; 95% CI: 1.223-1.417; rs3733197, P = 3.452e-06; OR = 1.193; 95% CI: 1.107-1.286); one SNP of TNFAIP3 associated with SLE (rs2230926, P = 1.502e-12; OR = 1.826; 95% CI: 1.545-2.157).
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21208380 |
2011 |
Lupus Erythematosus, Systemic
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|
0.880 |
GeneticVariation
|
BEFREE |
We confirmed the association of rs548234, rs2736340 and rs10516487 with SLE in Chinese Han and reinforced our hypothesis of their epistasis effect in regulating B-cell signaling in SLE.
|
26420661 |
2016 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
The strongest associations with SLE and BANK1 were at rs17266594 (corrected P-value=1.97 x 10(-5), odds ratio (OR)=1.22, 95% CI 1.12-1.34) and rs10516487 (corrected P-value=2.59 x 10(-5), OR=1.22, 95% CI 1.11-1.34).
|
19339986 |
2009 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
In addition, we observed a genetic interaction between BLK (rs2736340T/C, rs13277113A/G) and BANK1 (R61H and A383T) associated with susceptibility to SLE.
|
31134304 |
2019 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
Meta-analysis by autoimmune disease type revealed an association between both systemic lupus erythematosus and systemic sclerosis and the BANK1 rs10516487 T allele (OR = 1.294, 95% CI = 1.232-1.360, p<1.0 × 10-8, heterogeneity p = 0.556; OR = 1.102, 95% CI = 1.027-1.183, p = 0.017, heterogeneity p = 0.048).
|
28466820 |
2017 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASDB |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
To investigate 1 functional (rs17266594) and 2 potentially functional (rs10516487 and rs3733197) BANK1 variants, which were previously identified as systemic lupus erythematosus (SLE) susceptibility markers, to test whether they are associated with rheumatoid arthritis (RA).
|
19180476 |
2009 |
Multiple Sclerosis
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|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
Primary Sjögren's syndrome
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|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicated that the SNPs (rs2736340, rs13277113) of the FAM167A-BLK region, but not the BANK1 SNPs (rs4522865, rs17266594, and rs10516487), were associated with the development of pSS in Han Chinese.
|
23899688 |
2013 |
Psoriasis
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|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to determine the association between three functional SNPs of BANK1 (rs10516487, rs17266594 and rs3733197) with psoriasis in Southern Han Chinese population by determining their frequency in 242 patients with psoriasis and 317 healthy individuals.
|
21989138 |
2011 |
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, meta-analysis failed to indicate an association between the BANK1 rs10516487 T allele and rheumatoid arthritis (RA; OR = 1.006, 95% CI = 1.956-1.058, p = 0.819).
|
28466820 |
2017 |
Rheumatoid Arthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We did not find a significant association between RA and the rs10516487 and rs17266594 BANK1 polymorphisms.
|
19180476 |
2009 |
Systemic Scleroderma
|
|
0.020 |
GeneticVariation
|
BEFREE |
To determine whether the functional BANK1 variants rs3733197 and rs10516487 are associated with systemic sclerosis (SSc) in 2 European Caucasian populations and to investigate the putative gene-gene interactions between BANK1 and IRF5 as well as STAT4.
|
19877059 |
2009 |
Systemic Scleroderma
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant association of the rs10516487 G and rs17266594 T alleles with SSc susceptibility was observed (pooled OR=1.12, 95% CI 1.03 to 1.22; p=0.01 and pooled OR=1.14, 95% CI 1.05 to 1.25; p=0.003, respectively), whereas the rs3733197 genetic variant showed no statistically significant deviation.
|
19815934 |
2010 |