rs1051740, EPHX1

N. diseases: 56
Disease: Esophageal Neoplasms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.050 GeneticVariation BEFREE The association between the EPHX1 Tyr113His</span> and His139Arg polymorphisms and EC risk was pooled by odds ratios (ORs) together with their 95% confidence intervals (95%CIs). 25714851 2015
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.050 GeneticVariation BEFREE Meta-analysis showed that the Tyr113His polymorphism was a stronger power trend towards risk for esophageal cancer using a recessive model (CC versus CT+TT, OR = 1.204, 95%CI = 1.001-1.450, P = 0.049). 24615030 2014
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.050 GeneticVariation BEFREE This meta-analysis suggests that the p.Tyr113His and p.His139Arg polymorphisms in EPHX1 may not be associated with EC development. 24803829 2014
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.050 GeneticVariation BEFREE No significant association was found in either the allele or genotype models for Tyr1</span>13His or His139Arg polymorphism with risk for esophageal cancer</span>. 24222229 2013
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.050 GeneticVariation BEFREE Overall, meta-analysis showed that EPHX1 Tyr113His polymorphism was not associated with esophageal cancer risk under all genetic models. 23681797 2013