|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We, therefore, examined allele distributions of the Ser326Cys polymorphism in a case-control study of male lung cancer in Okinawa.
|
10744126 |
1999 |
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We, therefore, examined allele distributions of the Ser326Cys polymorphism in a case-control study of male lung cancer in Okinawa.
|
10744126 |
1999 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We, therefore, examined allele distributions of the Ser326Cys polymorphism in a case-control study of male lung cancer in Okinawa.
|
10744126 |
1999 |
|
Squamous cell carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Although our sample size was limited, these results indicate that the Ser326Cys variant may be related to squamous cell lung cancer susceptibility.
|
10744126 |
1999 |
|
Malignant neoplasm of esophagus
|
|
0.030 |
GeneticVariation
|
BEFREE |
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population.
|
11307145 |
2001 |
|
Esophageal carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population.
|
11307145 |
2001 |
|
Esophageal Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population.
|
11307145 |
2001 |
|
Squamous cell carcinoma of esophagus
|
|
0.020 |
GeneticVariation
|
BEFREE |
We investigated the association between Ser326Cys polymorphism and squamous-cell carcinoma of the esophagus among a Chinese population. hOGG1 gene polymorphism was detected by PCR-based single-strand conformation polymorphism and DNA sequencing among 201 normal controls and 196 patients with esophageal cancer from Linxian, China, a high-risk area for the disease.
|
11307145 |
2001 |
|
Stomach Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We examined the distribution of the hOGG1 Ser326Cys polymorphism and its presumed correlation with gastric cancer risk in two case-control studies of different ethnic groups in São Paulo, Brazil.
|
11448535 |
2001 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
We examined the distribution of the hOGG1 Ser326Cys polymorphism and its presumed correlation with gastric cancer risk in two case-control studies of different ethnic groups in São Paulo, Brazil.
|
11448535 |
2001 |
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.
|
11927502 |
2002 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.
|
11927502 |
2002 |
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.
|
11927502 |
2002 |
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that hOGG1 may play an important role in the repair of 8-OH-dG adducts in the aerodigestive tract and that the hOGG1 Ser326Cys polymorphism plays an important role in risk for smoking- and alcohol-related orolaryngeal cancer.
|
12117782 |
2002 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that hOGG1 may play an important role in the repair of 8-OH-dG adducts in the aerodigestive tract and that the hOGG1 Ser326Cys polymorphism plays an important role in risk for smoking- and alcohol-related orolaryngeal cancer.
|
12117782 |
2002 |
|
Adenocarcinoma of lung (disorder)
|
|
0.050 |
GeneticVariation
|
BEFREE |
In this study, polymorphisms in five genes involved in the metabolism of carcinogens or in the repair of damaged DNA in lung cells, NQO1-Pro187Ser, GSTT1-positive/null, GSTM1-positive/null, CYP1A1-Ile462Val, and OGG1-Ser326Cys, were examined for association with lung adenocarcinoma risk in a case-control study of 198 patients and 152 control subjects.
|
12163326 |
2002 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study supported the first study by Sugimura et al (Cancer Epidemiol Biomarkers Prev, 1999; 8: 669-674), that the association of OGG1 Ser326Cys polymorphism was limited for the risk of lung adenocarcinoma.
|
12164330 |
2002 |
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study supported the first study by Sugimura et al (Cancer Epidemiol Biomarkers Prev, 1999; 8: 669-674), that the association of OGG1 Ser326Cys polymorphism was limited for the risk of lung adenocarcinoma.
|
12164330 |
2002 |
|
Adenocarcinoma of lung (disorder)
|
|
0.050 |
GeneticVariation
|
BEFREE |
This study supported the first study by Sugimura et al (Cancer Epidemiol Biomarkers Prev, 1999; 8: 669-674), that the association of OGG1 Ser326Cys polymorphism was limited for the risk of lung adenocarcinoma.
|
12164330 |
2002 |
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant and increased risk of various types of cancer; (b) the XRCC1 R194W variant and reduced risk of various types of cancer; and (c) the BRCA2 N372H variant and increased risk of breast cancer.
|
12496039 |
2002 |
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant and increased risk of various types of cancer; (b) the XRCC1 R194W variant and reduced risk of various types of cancer; and (c) the BRCA2 N372H variant and increased risk of breast cancer.
|
12496039 |
2002 |
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant and increased risk of various types of cancer; (b) the XRCC1 R194W variant and reduced risk of various types of cancer; and (c) the BRCA2 N372H variant and increased risk of breast cancer.
|
12496039 |
2002 |
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant and increased risk of various types of cancer; (b) the XRCC1 R194W variant and reduced risk of various types of cancer; and (c) the BRCA2 N372H variant and increased risk of breast cancer.
|
12496039 |
2002 |
|
Colon Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results suggest that the hOGG1 Ser326Cys polymorphism is probably not a major contributor to individual colon cancer susceptibility overall, but the Cys/Cys genotype may alter the impact of some environmental factors on colon cancer development.
|
12717837 |
2003 |
|
Malignant tumor of colon
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results suggest that the hOGG1 Ser326Cys polymorphism is probably not a major contributor to individual colon cancer susceptibility overall, but the Cys/Cys genotype may alter the impact of some environmental factors on colon cancer development.
|
12717837 |
2003 |