|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed there was no association between hOGG1 rs1052133 and GC.
|
28415729 |
2017 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study and a meta-analysis.
|
26600527 |
2015 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to gastric cancer.
|
22799296 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our result could explain the association between hOGG1 Ser326Cys polymorphism and GC risk.
|
22294108 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Taken together, the results suggest that the hOGG1 Ser326Cys polymorphism may contribute to susceptibility to gastric cancer.
|
22343785 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis provided evidence that hOGG1 S326C genetic polymorphism was not associated with increased risk of gastric cancer.
|
22296498 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
No significant association was found for either allele or genotype with gastric cancer (odds ratio [OR]=0.96; 95% confidence interval [95% CI]: 0.82-1.13; P=0.66), and this was also the case after combining 326Ser/Cys and 326Ser/Ser genotypes together (OR=0.87; 95% CI: 0.63-1.20; P=0.40), or 326Cys/Cys and 326Ser/Cys together (OR=1.03; 95% CI: 0.87-1.22; P=0.72).
|
22471492 |
2011 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, bladder, prostate, esophageal, and gastric cancer were not detected.
|
22114677 |
2011 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
This variant decreased the gene promoter activity by approximately 17.8% (P = 0.041) and exhibited a synergistic effect with the missense mutation p.Ser326Cys of hOGG1 by enhancing susceptibility to gastric cancers.
|
21822670 |
2011 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To investigate the association between Ser326Cys human oxoguanine glycosylase 1 (hOGG1) polymorphism and atrophic gastritis and gastric cancer after Helicobacter pylori (H. pylori) eradication.
|
20845517 |
2010 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models.
|
20817763 |
2010 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
Although smokers and high salted tea drinkers themselves were at higher risk for gastric cancer (OR=8.975, P=0.0001; OR=14.778, P=0.0001), interaction with OGG1 Ser326Cys did not further modulate the risk.
|
20593951 |
2010 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group 1 (XRCC1, Arg194Trp and Arg399Gln), adenosine diphosphate ribosyl transferase (ADPRT, Val762Ala), 8-oxoguanine DNA glycosylase (OGG1, Ser326Cys) and apurinic/apyrimidinic endonuclease 1 (APE1, Asp148Glu) and evolution of H.pylori-associated precancerous gastric lesions, a population-based cohort study was conducted in Linqu County, a high-risk area of gastric cancer in China.
|
19147860 |
2009 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations.
|
15596047 |
2004 |
|
Malignant neoplasm of stomach
|
|
0.100 |
GeneticVariation
|
BEFREE |
We examined the distribution of the hOGG1 Ser326Cys polymorphism and its presumed correlation with gastric cancer risk in two case-control studies of different ethnic groups in São Paulo, Brazil.
|
11448535 |
2001 |