|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analysis.
|
24085357 |
2014 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
We demonstrated a novel, significant correlation between the hOGG1 Ser326Cys polymorphism and increased lung cancer susceptibility in Caucasians.
|
22855704 |
2013 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
The hOGG1 Ser326Cys polymorphism is associated with lung cancer risk, but there are limited data regarding an association between the APE1 Asp148Glu polymorphism and lung cancer.
|
23038158 |
2013 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies.
|
22540013 |
2012 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
Moreover, in subgroup analyses by cancer types, the stronger significant association between hOGG1 Ser326Cys polymorphism and lung cancer risk was found (Cys/Cys vs. Ser/Ser: OR = 1.29, 95%CI = 1.16-1.44, P<0.001; Cys/Cys vs. Cys/Ser+Ser/Ser: OR = 1.22, 95%CI = 1.12-1.33, P<0.001).
|
22114677 |
2012 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
In a nested case-cohort design we examined associations between urinary excretion of 8-oxoGua and risk of lung cancer as well as potential interaction with the OGG1 Ser326Cys polymorphism in a population-based cohort of 25,717 men and 27,972 women aged 50-64 years with 3-7 years follow-up.
|
22044660 |
2012 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
The effect of tobacco exposure and the OGG1 Ser326Cys showed also no significant risk for lung cancer.
|
19161591 |
2009 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
OGG1 S326C homozygote was suggested to be associated with lung cancer risk in Caucasians (homozygote OR, 1.34; 95% CI, 1.01-1.79) based on 2,569 cases and 4,178 controls from 4 studies but not in Asians.
|
18990748 |
2009 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study.
|
18155253 |
2008 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis.
|
18628426 |
2008 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China.
|
15284179 |
2007 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant Ser326Cys in OGG1 may be a risk factor for lung cancer, whereas a rare variant in OGG1 and germ line mutations in the corresponding mismatch repair gene MYH are risk factors for hereditary colon cancer.
|
16771692 |
2007 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer.
|
17015267 |
2007 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer in this study.
|
15896461 |
2005 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.
|
11927502 |
2002 |
|
Carcinoma of lung
|
0.100 |
GeneticVariation
|
BEFREE |
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility.
|
10744126 |
2000 |